Molecular basis of malaria pathogenesis and immunity at Københavns Universitet

MSc projects in malaria research on the molecular mechanisms of malaria pathogenesis and immunity

Background. Malaria caused by Plasmodium falciparum infections result in over 400.000 deaths and 200 million clinical cases each year. Malaria symptoms arise from the binding of parasite-infected red blood cells to human protein receptors on endothelial cell and immune cells mediated by variant protein families PfEMP1 and RIFINs exported onto the surface of the infected red blood cell. Immunity to malaria is acquired by the development of antibodies to PfEMP1 and RIFINs.

Projects1:
We are looking for MSc project students with experience and interest in Bioinformatics, Protein Modelling or strong experience in protein chemistry and structural biology for studies of molecular evolution, gene expression and antibody epitope mapping for developing new gene expression tools and guide malaria vaccine design.

Projects2:
We are looking for MSc students with experience and interest in cellular microbiology, parasitology and immunology to develop cellular methods and resolving the molecular process of parasite sequestration to human endothelium and for testing experimental vaccines inhibiting it.

The MSc projects include international collaborative activities and you will work closely with other members of our research team located at 11th floor at the Mærsk Building. Here, you will also be part of a larger research team cluster and shared laboratory facilities known as Centre for Medical Parasitology at ISIM, SUND, KU. (https://cmp.ku.dk/).

For more information, please contact Thomas Lavstsen at thomasl@sund.ku.dk

https://cmp.ku.dk/research/teamdiscovery/

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