PhD Positions in Bacterial Genetics
(1) Regulation of the Caulobacter cell cycle and DNA damage response by a toxin-antitoxin system
(2) Chemical genetics of Pseudomonas cell polarity determination mechanisms
Two three year PhD positions will be available in the group of Assistant Professor Clare Kirkpatrick at the Department of Biochemistry and Molecular Biology, University of Southern Denmark. The starting date for the successful candidates will be 1 May 2017 (Project 1) and 1 June 2017 (Project 2).
The research focus of the group will be on cell polarity and cell cycle regulation of the alpha- and gamma-proteobacteria, using Caulobacter crescentus and Pseudomonas aeruginosa as model systems and employing classical bacterial genetics, deep-sequencing genomics and high-throughput chemical-genetic screening (see for example Kirkpatrick et al, Nature Microbiology, 2016). Project 1 will follow up on the above-mentioned paper that describes the role of a toxin-antitoxin system in growth control of Caulobacter crescentus and aim to characterise the role of the toxin in regulation of the Caulobacter cell cycle, both under basal conditions and during DNA damage stress. Project 2 will study the molecular mechanisms by which certain drugs that were identified by high-throughput chemical screening are either more or less toxic to Pseudomonas mutants lacking certain polarity control factors compared to the wild type strain.
Candidates should have a Master’s degree in biochemistry, molecular biology, genetics, microbiology or a related field. Previous experience in microbiology is encouraged, but not mandatory; experience with analysis of deep-sequencing data is desirable. High intrinsic motivation and the capacity for independent work are mandatory. Applications should specify which project the candidate would prefer to work on, and why.
For further information please contact Clare Kirkpatrick , tel.: +33 682 61 60 99, e-mail:
Application, salary etc.
Appointment as a PhD Research Fellow is for three years. Employment stops automatically at the end of the period. The holder of the scholarship is not allowed to have other paid employment during the three-year period.
The successful applicant will be employed in accordance with the agreement of 10 November 2015 on salaried PhD scholars between the Ministry of Finance and AC (the Danish Confederation of Professional Associations).
The successful candidate will be enrolled at this university in accordance with faculty regulations and the Danish Ministerial Order on the PhD Programme at the Universities (PhD order).
The university encourages all persons interested in the position to apply, regardless of their age, gender, religious affiliation or ethnic background.
Application must be made in the form of a Declaration of Interest including the following:
• A research proposal/description of your approach to the above project (max one page excluding references)
• A letter stating your specific interest, motivation and qualifications for the project in question (max. two pages) (please attach this under box "Application form")
• Detailed CV, including personal contact information
• Copies of diplomas, Bachelor as well as Master’s degree, including transcript of notes/grades
• At least two signed reference letters. Should your referees wish to send their letters directly to us, please have them use e-mail: mentioning your name and the title of the position in the subject line. And please note that these also need to reach us before deadline.
Further information about the PhD-study can be found at the homepage of the University.
Applications must be submitted electronically using the link below. Attached files must be in Adobe PDF or Word format. Each box can only contain a single file of max. 10 Mb. We strongly recommend that you read How to apply before you apply.
Incomplete applications and applications received after the deadline will neither be considered nor evaluated. This also applies to reference letters.
Further information for international applicants about entering and working in Denmark.
01 marts 2017 (Application deadline: 01 march 2017)