PhD Position in Proteomics, 3D Cell Culture and Pancreatic Beta Cells Plasticity

Syddansk Universitet (SDU)

Ph.d. & forskning
Udlandet (øvrige)

The Department of Biochemistry and Molecular Biology at the University of Southern Denmark invites applications for a three-year position as a PhD fellow within the field of functional proteomics to be filled by 1 September 2017. Application deadline: 1 August 2017.

What are the molecular mechanisms that execute and control complex molecular networks that lead to emergence and maintenance of specific cellular lineages? How does a pancreatic beta cell reprogramme during the development of type 2 diabetes?

We will use 3D cell culturing to create functional beta-cell spheroids that are sensitive to glucose stimulation and are capable of surviving for prolonged periods e.g. four weeks. By manipulating the length of feeding and fasting periods in the cultures we will induce metabolic reprogramming of beta cells and characterise the dynamics of that process. We will use metabolomics, lipidomics and proteomics to study the signalling processes that initiate and propagate the reprogramming process.

Individuals with a Master's or Bachelor degree in molecular biology, biomedicine, biochemistry, cell biology or a related field are sought, with several of the following qualifications:

• Familiarity with mammalian cell culture techniques
• Experience in working with protein mass spectrometry and high resolution peptide and protein chromatography
• Expertise in computational biology and bioinformatics
• Ability to work independently
• Fluent in spoken and written English.

Place of work: Protein Research Group (Associate Professor Adelina Rogowska-Wrzesinska), Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark. The Protein Research Group is known internationally for its strong research environment in biomolecular mass spectrometry and functional proteomics and excellent infrastructure supported by the VILLUM Center for Bioanalytical Sciences and the PRO-MS research infrastructure supported by the Danish Ministry of Higher Education and Science.

This PhD position is part Sino Danish Center (SDC). During the period of employment at the University of Southern Denmark, the PhD student must spend a total of at least nine months at the laboratory of Chinese co-supervisor, Professor Fuquan Yang, at the Institute of Biophysics, Chinese Academy of Sciences, Beijing, China. The PhD student will be actively involved in the educational activities of the Master’s programmes at SDC and will obtain a double degree from the Danish and the Chinese University. The applicant cannot hold Chinese citizenship.

For further information please contact Associate Professor Adelina Rogowska-Wrzesinska, tel.: +45 6550 2351, e-mail: ().

Application, salary etc.
Appointment as a PhD Research Fellow is for three years. Employment stops automatically at the end of the period. The holder of the scholarship is not allowed to have other paid employment during the three-year period.

The successful applicant will be employed in accordance with the agreement of 10 November 2015 on salaried PhD scholars between the Ministry of Finance and AC (the Danish Confederation of Professional Associations).

The successful candidate will be enrolled at this university in accordance with faculty regulations and the Danish Ministerial Order on the PhD Programme at the Universities (PhD order).

The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.

Application must be made in the form of a Declaration of Interest including the following:
• A research proposal/description of your approach to the above project (max one page excluding references)
• A letter stating your specific interest, motivation and qualifications for the project in question (max. two pages) (please attach this under box "Application form")
• Detailed CV, including personal contact information
• Copies of diplomas, Bachelor as well as Master’s degree, including transcript of notes/grades
• At least two signed reference letters. Should your referees wish to send their letters directly to us, please have them use e-mail: mentioning your name and the title of the position in the subject line. And please note that these also need to reach us before deadline.

Further information about the PhD-study can be found at the homepage of the University.

Applications must be submitted electronically using the link below. Attached files must be in Adobe PDF or Word format. Each box can only contain a single file of max. 10 Mb. We strongly recommend that you read How to apply before you apply.

Incomplete applications and applications received after the deadline will neither be considered nor evaluated. This also applies to reference letters.

Further information for international applicants about entering and working in Denmark.


01 august 2017

Ansøgningsfrist d. 01.09.2017

Ph.d. & forskning
Udlandet (øvrige)
Kemi, Biotek & Materialer
Matematik, Fysik & Nano
Medicinal & Sundhed
Teknik & Teknologi
Forskning & Udvikling
Fejlmeld opslaget

Opslag oprettet d. 29.06.2017, sidst opdateret d. 29.06.2017

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